Transcription Factors in the Nervous System covers neural development, neuronal survival and function on the genetic level.

Features:

• Outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative disorders, such as Alzheimer's disease
• Details transcriptional control of neural development, brain function and transcriptional dysregulation induced neurological diseases
• Essential reading for neurobiologists, geneticists, biochemists, cell biologists, neurochemists and molecular biologists

Contents

Transcription Factors in Neural Development

• Roles of Hes bHLH Factors in Neuronal Development
• The Role of Pax6 in the Nervous System During Development and in Adulthood - Master Control Regulator or Modular Function?
• Phox2a and Phox2b Essential Transcription Factors or Neuron Specification and Differentiation
• Functions of LIM-Homedomain Proteins in the Development of the Nervous System
• Function of SRF and Ternary Complex Factors in the Nervous System
• RE-1 Silencing Transcription Factor (REST) - Regulation of Neuronal Gene Expression Via Modification of the Chromatin Structure
• Roles of Tix1 and TIX3 and Neuronal Activity in Controlling Glutamatergic Over GABAergic Cell Fates
• Transcriptional Control of the Development of Central Serotoneric Neurons
• Role of Nkx Homeodomain Factors in the Specification and Differentiation of Motor Neurons and Oligodendrocytes
• Sox Transcription Factors in Neural Development

Transcription Factors in Brain Function

• Role of CREB and CBP in Brain Function
• CCAAT Enhancer Binding Proteins in the Nervous System: Their Role in Development, Differentiation, Long-term Synaptic Plasticity and Memory
• Role of c-Jun in Brain Function
• Expression, Function, and Regulation of Transcription Factor MEF2 in Neurons
• RORalpha, an Orphan that Staggers the Mind
• Role of NF-kappaB in Brain Function
• Calcineurin/NFAT Signaling in Development and Function of the Nervous System
• Stimulus-Transcription Coupling in the Nervous System -
• The Zinc Finger Protein Egr-1

Transcription Factors in Neuronal Diseases

• The Presenilin/gamma-Secretase Complex Regulates Production of Transcriptional Factors: Effects of FAD Mutations
• Transcriptional Abnormalities in Huntington's Disease

Index

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