Transplantation of Neural Tissue into the Spinal Cord presents both recent and early results from various experiments where grafts of neuronal, glial and other tissues, as well as artificial materials, were placed into the spinal cord.

Transplantation of Neural Tissue into the Spinal Cord provides answers to many questions which could not be answered in the first edition, and accordingly all the chapters have been extensively rewritten and edited.

Contents

1. Anatomy and Physiology of the Spinal Cord

• Anatomy of the Spinal Cord
• Function of the Spinal Cord
• Neurotransmitters and Receptors in the Spinal Cord

2. Recovery of Function After Spinal Cord Injury

• The Effect of Spinal Transection on Behavior During Postnatal Development of the Rat and Kitten
• The Capacity of Spared Pathways for Sprouting Following Partial Injuries
• The Effect of Lesions to the Developing Mammalian Spinal Cord on the Neurons Innervating It
• Discussion: Possible Substrates for Recovery of Function After Injury

3. Recovery of Lost Spinal Cord Function by Facilitating the Spinal Cord Circuits Below the Lesion

• Spinal Cord Functions Controlled by Brain Stem Monoaminergic Connections
• Intraspinal Transplantation of Neural Cells of Supraspinal Origin

4. Encouraging Regeneration of Host Neurons: The Use of Peripheral Nerve Bridges, Glial Cells or Biomaterials

• Grafting Peripheral Nerves into the Spinal Cord
• Transplantation of Schwann Cells and Olfactory Ensheathing Cells into Lesioned Spinal Cord to Enhance Regeneration
• Implantation of Various Materials into the Spinal Cord

5. Encouraging Regeneration of Host Neurons: Transplantation of Neural Tissues into the Injured Spinal Cord Grafts of Embryonic Neural Tissue

• Survival and Development of Embryonic Grafts in the Spinal Cord
• Integration of the Grafted Tissue with the Host Spinal Cord
• Graft-Induced Improvement of Function
• The Use of Other Cell Types of Promote Recovery After Spinal Cord Lesions

Index

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