Transcription Factors contains in-depth information regarding the role of transcription factors as key players in the execution of the genomic program of any given cell.
Many of the chapters focus on the role of transcription factors in cellular transformation and cancer, other chapters highlight the contributions of transcription factors to inflammatory responses or xenobiotic responses.
Moreover, Transcription Factors illustrates how a viral transcription factor interferes with the physiology of its host cell and finally points out how much exciting research transcription factor biology still has to offer.
Contents
An Introduction to Transcription Factors
- Mechanisms of Transcriptional Activation in Eukaryotes
- Multiple Mechanisms of Transcriptional Repression in Eukaryotes
- Genomic Approaches to the Study of Transcription Factors
Transcription Factors in Pathophysiology
- Biological Roles of the STAT Family in Cytokine Signaling
- Members of the T-Cell Factor Family of DNA-Binding Proteins
and Their Roles in Tumorigenesis
- Transcription Factors in the Control of Tumor Development
and Progression by TGF-b Signaling
- The p53 Transcription Factor as Therapeutic Target in Cancer
- The Role of Ets Transcription Factors in Mediating Cellular
Transformation
- Function of the E2F Transcription Factor Family
During Normal and Pathological Growth
- c-Myc in Cellular Transformation and Cancer
- NF-kB: Critical Regulator of Inflammation and the Immune Response
- Hepatitis B Virus X Protein: Structure–Function
Relationships and Role in Viral Pathogenesis
- Regulation of Xenobiotic Detoxification by PXR, CAR, GR, VDR
and SHP Receptors: Consequences in Physiology
Exogenous Control of Transcription Factor Activity
- Potential of Transcription Factor Decoy Oligonucleotides
as Therapeutic Approach
- Selective Estrogen Receptor Modulators
as Therapeutic Agents in Breast Cancer Treatment
- Artificial Zinc Finger Peptides: A Promising Tool in Biotechnology and Medicine
- Tetracycline-Controlled Transactivators and Their Potential Use
in Gene Therapy Applications
- Modulating Transcription with Artificial Regulators
Index
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