Major Bladder Cancer Handbook from C.H.I.P.S.

Textbook of Bladder Cancer
edited by Seth P. Lerner

Features of Textbook of Bladder Cancer:

  • comprehensive reference, drawing on the expertise of international leaders in the field
  • covers everything from epidemiology, pathology, and diagnosis to the treatment of both superficial and invasive bladder cancers
  • contains more than 250 high quality color images



  1. Epidemiology of bladder cancer
  2. Occupational risk factors
  3. Familial bladder cancer
  4. Genetic susceptibility to bladder cancer


  1. Urothelial carcinoma and its variants
  2. WHO/ISUP grading system
  3. Urothelial bladder tumor pathology
  4. Non-urothelial tumors

Molecular Biology

  1. Gene discovery
  2. Molecular biology of bladder cancer: cell cycle alterations
  3. Cytogenetics of urothelial neoplasis
  4. Gene microarrays
  5. Molecular biology of invasive and metastatic urothelial cancer
  6. Animal models of bladder cancer
  7. Animal models: naturally occurring canine urinary bladder cancer


  1. Cystoscopy
  2. Florescence endoscopy
  3. Imaging in the assessment of urinary bladder carcinoma
  4. Cytology and DNA ploidy
  5. Voided urine markers
  6. Staging
  7. Etiology and management of urothelial tumors of the renal pelvis and ureter
  8. Early detection for bladder cancer
  9. Natural history of stages Ta, T1, and Tis urothelial cancer in the urinary bladder
  10. Risk stratification of Ta, Tis, T1 cancer
  11. Issues in staging of Ta, Tis, T1 bladder cancers


  1. Transurethral resection of bladder tumors
  2. Laser ablation and other technology
  3. Perioperative instillation of chemotherapeutic drugs
  4. The role of intravesical chemotherapy in the treatment of bladder cancer
  5. Intravesical chemotherapy of superficial bladder cancer: optimization and novel agents
  6. Intravesical immunothrapy: BCG
  7. Mode of action of BCG and rationale for combination immunotherapy
  8. Marker tumor concept: ethical issues
  9. The use of the marker tumor concept in Ta, T1 bladder cancer: is it justified?
  10. Photodynamic therapy
  11. G3T1 bladder carcinoma
  12. What to do when BCG fails
  13. Chemoprevention of superficial bladder cancer
  14. Surrogate endpoint biomarkers
  15. Follow-up strategies in superficial bladder cancer


  1. The natural history of invasive bladder cancer
  2. Selection and perioperative management of patients undergoing radical cystectomy and urinary reconstruction
  3. Radical cystectomy—technique and outcomes
  4. Cystectomy in the female
  5. Nerve-sparing radical cystectomy
  6. Laparoscopic radical cystectomy and urinary diversity
  7. Role of extended pelvic lymphadenectomy
  8. Role of sentinel node detection
  9. Management of the urethra in the cystectomy patient
  10. Rold of radical cystectomy in patients with unresectable and/or locoregionally metastatic bladder cancer

Primary Bladder Sparing Therapy

  1. Radical TURBT
  2. Partial cystectomy
  3. Optimal radiotherapy for bladder cancer
  4. Trimodality therapy in the management of muscle-invasive bladder cancer: a selective organ-preserving approach

Urinary Tract Reconstruction

  1. Orthotopic neobladder
  2. Continent cutaneous diversion
  3. Noncontinent urinary diversion
  4. Metabolic aspects of diversion
  5. Psychosocial and quality-of-life issues
  6. Tissue engineering of the bladder

Treatment of Regionally Advanced and Metastatic Bladder Cancer

  1. Clinical trial design
  2. Neo-adjuvant chemotherapy in the treatment of muscle-invasive bladder cancer
  3. Adjuvant chemotherapy for invasive bladder cancer
  4. Treatment of metastatic cancer
  5. Special considerations in the elderly patient

Novel and Emerging Therapy

  1. Targeted therapy for bladder cancer
  2. Bladder cancer gene therapy

Treatment of Non-TCC

  1. Treatment of non-TCC adenocarcinoma/sarcoma
  2. Treatment of squamous cell carcinoma
  3. Pediatric bladder tumors


  1. Bladder cancer internet resources
  2. Support groups
  3. Education and counseling of the cystectomy patient


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Textbook of Bladder Cancer
edited by Seth P. Lerner
2006 • 816 pages • $788.95 + shipping
Texas residents please add 6.75 % sales tax

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