Viral Hepatitis represents the first comprehensive reference book on viral hepatitis.

Viral Hepatitis has been completely revised and updated to address the recent advances in diagnosis and treatment.

Chapters include:

• Biology of liver stem cells and liver regeneration
• Basic hepatic immunology and molecular virology of hepatitis A, B, C, D and E
• Host immune response
• Hepatitis E as a zoonosis and the latest results of the hepatitis E vaccine trail

Viral Hepatitis offers an ideal reference for all healthcare professionals involved in the research and patient care of this disease.

Contents

Introduction to Liver Biology

1. Liver stem cells in persistent viral infection, liver regeneration and Cancer
2. The role of the liver in the immune response

Clinical Aspects of Viral Hepatitis

3. Clinical Features of Hepatitis
4. Diagnosis
5. Evolution of hepatitis viruses

Hepatitis A Virus

6. Structure and Molecular Virology
7. Epidemiology
8. Natural History and Experimental Models
9. Prevention

Hepadnaviridae

10. Structure and Molecular Virology
11. Epidemiology of Hepatitis B
12. Avihepadnaviridae
13. Woodchuck Hepadnaviruses
14. Molecular Variants of Hepatitis B Virus - surface antigen
15. Molecular Variants of Hepatitis B Virus - core antigen
16. Natural History of Chronic Hepatitis B and Hepatocellular Carcinoma
17. Hepatocellular Carcinoma: Molecular Aspects in hepatitis B
18. Pathogenesis of Chronic Hepatitis B - animal studies
19. Pathogenesis of Chronic Hepatitis B - human studies
20. Treatment of Chronic Hepatitis B
21. Management of drug resistant variants
22. Liver Transplantation in the Management of Chronic Viral Hepatitis
23. Protection against hepatitis B

Hepatitis C Virus

24. Structure and Molecular Virology
25. Epidemiology
26. Immune response to HCV in acute & chronic infection
27. Chimpanzee model of HCV
28. Autoimmune disorders associated with hepatitis C
29. CNS complication of HCV infection
30. In vitro replication models of HCV
31. Small animal models of Hepatitis C
32. Progression of Hepatitis C
33. Natural History of Chronic Hepatitis C and Hepatocellular Carcinoma
34. Treatment of Chronic Hepatitis C
35. New drugs for management of hepatitis C
36. Prevention of hepatitis C

Hepatitis D Virus

37. Structure and Molecular Virology
38. Epidemiology Natural History
39. Treatment of Hepatitis D

Hepatitis E Virus

40. Structure and Molecular biology
41. Hepatitis E as a Zoonotic Disease
42. Epidemiology, Natural History and Experimental Models Diagnosis
43. Prevention

Clinical Aspects of Viral Liver Disease

44. Etiology of Fulminant Hepatitis
45. Treatment of Fulminant Hepatitis
46. Transfusion-Associated Hepatitis
47. Hepatitis and Hemophila
48. Occupational Aspects of Hepatitis
49. Neonatal and Pediatric Infection
50. Management of Hepatocellular Carcinoma
51. Application of Molecular Biology to the Diagnosis of Viral Hepatitis
52. Hepatitis in HIV-infected Persons
53. Treatment of extra-hepatic diseases caused by HBV & HCV
54. The Histologist's Role in Diagnosis and Management of Chronic Hepatitis B & C
55. Disinfection and Sterilization
56. Mechanisms of interferon resistance
57. Novel cytokines for all hepatitis
58. New in vitro testing systems
59. New vaccine technology (oral vaccines/adjuvants)
60. Safety of hepatitis vaccines
61. History of hepatitis

Index

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